Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10413107 | 0.99 | TSHR (0.44) | TSHRKMT2APOLBMEN1KDM4E | |
| SCHEMBL28957583 | 0.82 | MEN1 (0.47) | TSHRKMT2APOLBMEN1KDM4E | |
| SCHEMBL12844407 | 0.80 | MAPT (0.48) | TSHRKMT2APOLBMEN1KDM4E | |
| SCHEMBL762893 | 0.73 | KMT2A (0.56) | TSHRKMT2APOLBMEN1KDM4E | |
| SCHEMBL14944881 | 0.72 | KDM4E (0.55) | TSHRKMT2APOLBMEN1KDM4E | |
| SCHEMBL7300063 | 0.69 | SIGMAR1 (0.44) | — | |
| SCHEMBL20780757 | 0.68 | HSD17B10 (0.42) | TSHRKMT2APOLBMEN1KDM4E | |
| SCHEMBL25399698 | 0.67 | MAPT (0.57) | TSHRKMT2APOLBMEN1KDM4E | |
| SCHEMBL7718402 | 0.67 | KDM4E (0.52) | TSHRKMT2APOLBMEN1KDM4E | |
| SCHEMBL4678156 | 0.67 | KDM4E (0.52) | TSHRKMT2APOLBMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304789-B1 | BENZIMIDAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-03-17 | — | — | EP | disclosed |
| EP-0304789-A2 | Benzimidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-03-01 | — | — | EP | disclosed |