Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.50 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29402191 | 0.94 | CASP1 (0.47) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL6706623 | 0.92 | BCHE (0.54) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL31047751 | 0.92 | KYNU (0.49) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL10313730 | 0.92 | CASP1 (0.47) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL31614372 | 0.92 | CASP1 (0.47) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL7130286 | 0.88 | BCHE (0.48) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL13418028 | 0.86 | CASP1 (0.43) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL29401031 | 0.86 | KLK7 (0.47) | BCHEACHECTSLCTSSCTSK | |
| SCHEMBL7299898 | 0.85 | ACE (0.39) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL28704605 | 0.85 | BCHE (0.58) | BCHEACHECACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352815-B1 | PRODRUGS OF DOPAMINE | ZAMBON GROUP S.p.A. (IT) | 1993-05-19 | — | — | EP | disclosed |
| EP-0352815-A1 | Prodrugs of dopamine | ZAMBON GROUP S.p.A. (IT) | 1990-01-31 | — | — | EP | disclosed |