SCHEMBL31047751

SCHEMBL31047751

COC(=O)[C@H](CCC(=O)ON1C(=O)CCC1=O)NC(=O)OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KYNU Q16719 1/20 0.49
SIRT2 Q8IXJ6 1/20 0.48
SIRT1 Q96EB6 1/20 0.48
SIRT3 Q9NTG7 1/20 0.48
ALDH1A1 P00352 1/20 0.47
ALOX15 P16050 1/20 0.47
CASP1 P29466 2/20 0.46
BCHE P06276 2/20 0.45
ACHE P22303 2/20 0.45
CACNA1F O60840 1/20 0.45
CACNA1D Q01668 1/20 0.45
CACNA1S Q13698 1/20 0.45
CACNA1C Q13936 1/20 0.45
CTSK P43235 6/20 0.44
CTSL P07711 3/20 0.43
CTSS P25774 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29402191 0.94 CASP1 (0.47) CASP1BCHEACHECACNA1FCACNA1D
SCHEMBL10313730 0.94 CASP1 (0.47) CASP1BCHEACHECACNA1FCACNA1D
SCHEMBL31614372 0.94 CASP1 (0.47) CASP1BCHEACHECACNA1FCACNA1D
SCHEMBL7299901 0.92 BCHE (0.50) SIRT2SIRT1SIRT3ALDH1A1CASP1
SCHEMBL13418028 0.88 CASP1 (0.43) CASP1BCHEACHECACNA1FCACNA1D
SCHEMBL6706623 0.88 BCHE (0.54) SIRT2SIRT1SIRT3ALDH1A1CASP1
SCHEMBL7130286 0.86 BCHE (0.48) SIRT2SIRT1SIRT3ALDH1A1BCHE
SCHEMBL29401031 0.86 KLK7 (0.47) BCHEACHECTSKCTSLCTSS
SCHEMBL2777934 0.86 SYK (0.46) CASP1BCHEACHECACNA1FCACNA1D
SCHEMBL7998762 0.86 CASP1 (0.50) CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124317-A2 Antibody Drug Conjugates BEONE MEDICINES I GMBH (CH) 2026-05-07 US disclosed
US-20250135026-A1 Antibody Drug Conjugates BEIGENE SWITZERLAND GMBH (CH) 2025-05-01 US disclosed
CN-118450907-A Antibody drug conjugates 百济神州有限公司 2024-08-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124317-A2 Antibody Drug Conjugates SLC3A2, SLC7A1, SLC43A1 KYNU 1108/4885SIRT2 1049/4885SIRT1 1307/4885
US-20250135026-A1 Antibody Drug Conjugates CD22, FCGR2A, FCGR3B KYNU 4202/4885SIRT2 2339/4885SIRT1 3465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.