Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049631 | 0.85 | MEN1 (0.53) | MEN1KMT2AHPGDKDM4EMAPT | |
| SCHEMBL7301777 | 0.82 | TOP2A (0.53) | MEN1KMT2AKDM4EMAPTTDP1 | |
| SCHEMBL7308078 | 0.78 | KDM4E (0.51) | KDM4EMAPTTDP1GAATOP2A | |
| SCHEMBL16696075 | 0.78 | KDM4E (0.45) | MEN1KMT2AHPGDKDM4EMAPT | |
| SCHEMBL29835225 | 0.77 | KDM4E (0.48) | MEN1KMT2AHPGDKDM4EMAPT | |
| SCHEMBL9831365 | 0.77 | MEN1 (0.52) | MEN1KMT2AHPGDKDM4EMAPT | |
| SCHEMBL15383209 | 0.76 | MAPT (0.57) | KMT2AKDM4EMAPTTDP1GAA | |
| SCHEMBL8045002 | 0.76 | ALDH1A1 (0.48) | MEN1KMT2AHPGDKDM4ETDP1 | |
| SCHEMBL8044536 | 0.75 | NPC1 (0.44) | MEN1KMT2AHPGDKDM4ETDP1 | |
| SCHEMBL8047377 | 0.75 | KMT2A (0.49) | MEN1KMT2AHPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304560-A | Treating CNS disorders; dopamine receptor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0481342-A1 | Quinazoline derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |