Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045002 | 0.93 | ALDH1A1 (0.48) | NPC1ALDH1A1KDM4EGAAGLA | |
| SCHEMBL8049631 | 0.90 | MEN1 (0.53) | NPC1ALDH1A1KDM4EGAAGLA | |
| SCHEMBL8047377 | 0.85 | KMT2A (0.49) | ALDH1A1KDM4EGAAGLAMEN1 | |
| SCHEMBL8035251 | 0.81 | MEN1 (0.50) | NPC1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8049795 | 0.81 | ALDH1A1 (0.44) | NPC1ALDH1A1KDM4EGAAGLA | |
| SCHEMBL8035690 | 0.80 | PLAU (0.52) | NPC1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10487899 | 0.79 | ALDH1A1 (0.56) | NPC1ALDH1A1KDM4EGAAGLA | |
| SCHEMBL8053284 | 0.78 | MEN1 (0.51) | NPC1ALDH1A1KDM4EGAAGLA | |
| SCHEMBL8432960 | 0.77 | MEN1 (0.56) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL9573768 | 0.77 | KMT2A (0.51) | NPC1ALDH1A1KDM4EGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789020-B1 | Process for producing dioxoquinazolines | SUMITOMO CHEMICAL CO (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5780628-A | Process for producing dioxoquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0789020-A1 | Process for producing dioxoquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-13 | — | — | EP | disclosed |