Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CD38 | P28907 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488011 | 0.86 | SMN1; SMN2 (0.46) | KDM4EMAPTTDP1TSHRALDH1A1 | |
| SCHEMBL7301777 | 0.82 | TOP2A (0.53) | KDM4EMAPTTOP2ATDP1LTA4H | |
| SCHEMBL5262043 | 0.80 | ALDH1A1 (0.45) | KDM4EMAPTALDH1A1GAA | |
| SCHEMBL7300293 | 0.78 | MEN1 (0.49) | KDM4EMAPTTOP2ATDP1ALDH1A1 | |
| SCHEMBL11317541 | 0.78 | MAPT (0.54) | KDM4EMAPTTOP2ALTA4HALDH1A1 | |
| SCHEMBL9830719 | 0.77 | ALDH1A1 (0.54) | KDM4EMAPTTDP1TSHRALDH1A1 | |
| SCHEMBL9432244 | 0.76 | MAPT (0.41) | KDM4EMAPTALDH1A1GAACD38 | |
| SCHEMBL9432247 | 0.76 | MAPT (0.41) | KDM4EMAPTALDH1A1GAACD38 | |
| SCHEMBL10487877 | 0.76 | SMN1; SMN2 (0.46) | KDM4EMAPTTDP1TSHRALDH1A1 | |
| SCHEMBL688699 | 0.76 | ALDH1A1 (0.58) | KDM4EMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304560-A | Treating CNS disorders; dopamine receptor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0481342-A1 | Quinazoline derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |