Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.60 |
| ▸ | PPARA | Q07869 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302122 | 0.83 | RAB9A (0.56) | PPARGPPARARAB9AMAPTNPC1 | |
| SCHEMBL16742493 | 0.81 | FPR2 (0.58) | PPARGPPARARAB9ANPC1MEN1 | |
| SCHEMBL19563266 | 0.81 | FPR2 (0.58) | PPARGPPARARAB9ANPC1MEN1 | |
| SCHEMBL23397877 | 0.78 | ACE (0.41) | PPARGPPARAMAPTCYP1A2MEN1 | |
| SCHEMBL7308247 | 0.76 | KMT2A (0.60) | PPARGPPARARAB9AMAPTNPC1 | |
| SCHEMBL4432278 | 0.76 | MGLL (0.65) | RAB9AMAPTNPC1CYP1A2MEN1 | |
| SCHEMBL30207797 | 0.76 | MGLL (0.65) | RAB9AMAPTNPC1CYP1A2MEN1 | |
| SCHEMBL3046273 | 0.76 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL11396978 | 0.76 | KDM4E (0.60) | RAB9AMAPTNPC1CYP1A2MEN1 | |
| SCHEMBL7301106 | 0.76 | RAB9A (0.52) | RAB9AMAPTNPC1CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |