Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299853 | 0.92 | CCNC (0.34) | PDE4BPDE4DPDE7APDE7BSMN1; SMN2 | |
| SCHEMBL7291279 | 0.89 | ADORA2B (0.31) | MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL7292134 | 0.88 | MAPT (0.35) | MAPT | |
| SCHEMBL7290178 | 0.86 | CYP11B2 (0.32) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8085331 | 0.85 | HSD17B10 (0.38) | MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL7289644 | 0.85 | CHUK (0.34) | PDE4BPDE4DPDE7APDE7B | |
| SCHEMBL7294466 | 0.84 | CCNC (0.33) | — | |
| SCHEMBL7291740 | 0.83 | MEN1 (0.33) | MEN1MAPTKMT2A | |
| SCHEMBL7291070 | 0.81 | CCNC (0.35) | MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL7292141 | 0.81 | CCNC (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308792-B1 | AZACHROMANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1993-07-28 | — | — | EP | disclosed |
| US-4931454-A | Azachroman derivatives with effects on the cardiovascular system | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-06-05 | — | — | US | disclosed |
| EP-0308792-A2 | Azachromane derivatives | MERCK PATENT GmbH (DE) | 1989-03-29 | — | — | EP | disclosed |