Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.59 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 2/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300843 | 1.00 | PREP (0.59) | PREPACEALDH1A1FKBP1AKMT2A | |
| SCHEMBL7272783 | 0.84 | PREP (0.66) | PREPACEALDH1A1FKBP1AKMT2A | |
| SCHEMBL11764594 | 0.83 | PREP (0.71) | PREPACEALDH1A1FKBP1AKMT2A | |
| SCHEMBL2228388 | 0.83 | PREP (0.71) | PREPACEALDH1A1FKBP1AKMT2A | |
| SCHEMBL2082597 | 0.82 | PREP (0.69) | PREPACEALDH1A1FKBP1AKMT2A | |
| SCHEMBL11033242 | 0.81 | PREP (0.68) | PREPACEALDH1A1FKBP1AKMT2A | |
| SCHEMBL9518270 | 0.81 | PREP (0.68) | PREPACEALDH1A1FKBP1AKMT2A | |
| SCHEMBL7304424 | 0.81 | PREP (0.59) | PREPKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL7296585 | 0.81 | PREP (0.59) | PREPKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL7404507 | 0.81 | PREP (0.59) | PREPKMT2ACYP3A4MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468469-A2 | Proline derivatives | Japan Tobacco Inc. (JP) | 1992-01-29 | — | — | EP | claimed |
| EP-0468469-A2 | Proline derivatives | Japan Tobacco Inc. (JP) | 1992-01-29 | — | — | EP | disclosed |