Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 2/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | CPA3 | P15088 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297996 | 0.79 | PPARG (0.39) | TSHRCYP1A2KDM4EMEN1KMT2A | |
| SCHEMBL372276 | 0.78 | CYP1A2 (0.57) | TSHRCYP1A2KDM4EMEN1KMT2A | |
| SCHEMBL25816145 | 0.78 | CYP1A2 (0.57) | TSHRCYP1A2KDM4EMEN1KMT2A | |
| SCHEMBL2456546 | 0.78 | MEN1 (0.58) | TSHRCYP1A2KDM4EMEN1KMT2A | |
| SCHEMBL10525325 | 0.78 | CYP1A2 (0.57) | TSHRCYP1A2KDM4EMEN1KMT2A | |
| SCHEMBL10692703 | 0.78 | CYP1A2 (0.57) | TSHRCYP1A2KDM4EMEN1KMT2A | |
| SCHEMBL20563859 | 0.76 | CYP1A2 (0.55) | TSHRCYP1A2KDM4EMEN1KMT2A | |
| SCHEMBL28306686 | 0.75 | CYP1A2 (0.54) | TSHRCYP1A2KDM4EMEN1KMT2A | |
| SCHEMBL6387359 | 0.75 | POLB (0.55) | TSHRCYP1A2KDM4EMEN1KMT2A | |
| SCHEMBL6743921 | 0.75 | CYP2C9 (0.59) | TSHRCYP1A2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341602-A2 | Renin-inhibiting functionalized peptidyl aminodiols and - triols | ABBOTT LABORATORIES (US) | 1989-11-15 | — | — | EP | disclosed |