Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CPA1 | P15085 | 2/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | CPA3 | P15088 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KYNU | Q16719 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21405660 | 0.81 | LMNA (0.40) | CYP1A2TSHRALDH1A1HSD17B10POLB | |
| SCHEMBL31357901 | 0.81 | LMNA (0.40) | CYP1A2TSHRALDH1A1HSD17B10POLB | |
| SCHEMBL372487 | 0.81 | LMNA (0.40) | CYP1A2TSHRALDH1A1HSD17B10POLB | |
| SCHEMBL19951679 | 0.79 | PPARG (0.39) | CYP1A2TSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1162115 | 0.79 | PPARG (0.39) | CYP1A2TSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL10435608 | 0.79 | CYP2C19 (0.42) | CYP1A2TSHRKDM4EMEN1KMT2A | |
| SCHEMBL28306686 | 0.79 | CYP1A2 (0.54) | CYP1A2TSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL10692703 | 0.78 | CYP1A2 (0.57) | CYP1A2TSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1644947 | 0.78 | FFAR1 (0.47) | CYP1A2TSHRKDM4EALDH1A1CPA1 | |
| SCHEMBL10523946 | 0.78 | GABBR2 (0.42) | CYP1A2TSHRKDM4EPOLBCPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749373-B | Rubber additive and preparation and application thereof | 同济大学 | 2020-06-26 | — | — | CN | disclosed |
| EP-2409569-B1 | Method for administering GLP-1 molecules | EMISPHERE TECH INC (US) | 2017-08-16 | — | — | EP | disclosed |
| EP-1478233-B1 | METHOD FOR ADMINISTERING GLP-1 MOLECULES | EMISPHERE TECH INC (US) | 2016-11-09 | — | — | EP | disclosed |
| EP-1015008-B1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2015-08-05 | — | — | EP | disclosed |
| US-20150202296-A1 | METHOD FOR ADMINISTERING GLP-1 MOLECULES | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2015-07-23 | — | — | US | disclosed |
| US-8785381-B2 | Oral GLP-1 formulations | EMISPHERE TECHNOLOGIES, INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-20140005106-A1 | METHOD FOR ADMINISTERING GLP-1 MOLECULES | EMISPHERE TECHNOLOGIES, INC. (US) | 2014-01-02 | — | — | US | disclosed |
| US-8492330-B2 | Formulation comprising GLP-1 | EMISPHERE TECHNOLOGIES, INC. (US) | 2013-07-23 | — | — | US | disclosed |
| EP-2409569-A2 | Method for administering GLP-1 molecules | Emisphere Technologies, Inc. (US) | 2012-01-25 | — | — | EP | disclosed |
| US-20110178006-A1 | METHOD FOR ADMINISTERING GLP-1 MOLECULES | EMISPHERE TECHNOLOGIES, INC. (US) | 2011-07-21 | — | — | US | disclosed |
| US-5879681-A | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLGIES INC. (US) | 1999-03-09 | — | — | US | disclosed |
| US-5876710-A | DRUG DELIVERY; USING A BROMINATED BENZAMIDE COMPOUND | EMISPHERE TECHNOLOGIES INC. (US) | 1999-03-02 | — | — | US | disclosed |
| US-5804688-A | 6-N-(3,5-DICHLORO-2-HYDROXYBENZOYL)AMINOCAPROIC ACID | EMISPHERE TECHNOLOGIES, INC. (US) | 1998-09-08 | — | — | US | disclosed |
| WO-1998034632-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 1998-08-13 | — | — | WO | disclosed |
| US-5776888-A | 3-(DIMETHOXYBENZOYLAMINOPHENYL) PROPIONIC ACID | EMISPHERE TECHNOLOGIES, INC. (US) | 1998-07-07 | — | — | US | disclosed |
| US-5773647-A | USING A AROMATIC COMPOUND CONTAINING AMIDE AND CARBOXY GROUPS | EMISPHERE TECHNOLOGIES, INC. (US) | 1998-06-30 | — | — | US | disclosed |
| US-5583020-A | IONIZATION; DRUG DELIVERY | RIBOZYME PHARMACEUTICALS, INC. (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0669926-A1 | PERMEABILITY ENHANCERS FOR IONIC THERAPEUTIC POLYMERS | RIBOZYME PHARMACEUTICALS, INC. (US) | 1995-09-06 | — | — | EP | disclosed |
| WO-1994012516-A9 | PERMEABILITY ENHANCERS FOR IONIC THERAPEUTIC POLYMERS | — | 1994-08-04 | — | — | WO | disclosed |
| WO-1994012516-A1 | PERMEABILITY ENHANCERS FOR IONIC THERAPEUTIC POLYMERS | RIBOZYME PHARMACEUTICALS, INC. (US) | 1994-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150202296-A1 | METHOD FOR ADMINISTERING GLP-1 MOLECULES | GLP1R, GIPR, GPR119 | CYP1A2 2415/4885TSHR 125/4885KDM4E 4046/4885 |
| US-20110178006-A1 | METHOD FOR ADMINISTERING GLP-1 MOLECULES | GLP1R, GIPR, GPR119 | CYP1A2 2415/4885TSHR 125/4885KDM4E 4046/4885 |
| US-20140005106-A1 | METHOD FOR ADMINISTERING GLP-1 MOLECULES | GLP1R, GIPR, GPR119 | CYP1A2 2415/4885TSHR 125/4885KDM4E 4046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.