SCHEMBL10692703

SCHEMBL10692703

CC(C)c1ccccc1C(CC(=O)O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.57
TSHR P16473 1/20 0.57
KDM4E B2RXH2 2/20 0.53
ALDH1A1 P00352 3/20 0.48
HSD17B10 Q99714 2/20 0.48
POLB P06746 2/20 0.46
USP2 O75604 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
GAA P10253 1/20 0.45
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
CPA1 P15085 2/20 0.42
CPB1 P15086 1/20 0.42
CPA3 P15088 1/20 0.42
CPB2 Q96IY4 1/20 0.42
LMNA P02545 1/20 0.41
GABRA1 P14867 2/20 0.41
GABRB2 P47870 1/20 0.41
FFAR1 O14842 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10696233 0.84 TSHR (0.53) CYP1A2TSHRKDM4EALDH1A1HSD17B10
SCHEMBL19946640 0.83 CRHBP (0.44) CYP1A2TSHRHSD17B10KMT2AMEN1
SCHEMBL10525325 0.81 CYP1A2 (0.57) CYP1A2TSHRKDM4EALDH1A1HSD17B10
SCHEMBL20563859 0.80 CYP1A2 (0.55) CYP1A2TSHRKDM4EALDH1A1HSD17B10
SCHEMBL6387359 0.79 POLB (0.55) CYP1A2TSHRKDM4EALDH1A1HSD17B10
SCHEMBL31483446 0.78 CYP1A2 (0.50) CYP1A2TSHRKDM4EALDH1A1HSD17B10
SCHEMBL2456546 0.78 MEN1 (0.58) CYP1A2TSHRKDM4EALDH1A1HSD17B10
SCHEMBL25816145 0.78 CYP1A2 (0.57) CYP1A2TSHRKDM4EALDH1A1HSD17B10
SCHEMBL372276 0.78 CYP1A2 (0.57) CYP1A2TSHRKDM4EALDH1A1HSD17B10
SCHEMBL7300866 0.78 TSHR (0.57) CYP1A2TSHRKDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0253501-A2 N-disubstituted cycloalkylmethyl amines useful as fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-01-20 EP disclosed