Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.50 |
| ▸ | RXRB | P28702 | 4/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.44 |
| ▸ | RXRG | P48443 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303640 | 0.93 | ITGB3 (0.70) | ITGB3ITGA2BFFAR1RXRBRXRA | |
| SCHEMBL7308788 | 0.87 | ITGB3 (0.81) | ITGB3ITGA2BRXRB | |
| SCHEMBL7307011 | 0.84 | ITGB3 (0.62) | ITGB3ITGA2BFFAR1RXRBCYP4F2 | |
| SCHEMBL7300961 | 0.81 | ITGB3 (0.92) | ITGB3ITGA2BRXRBRXRARXRG | |
| SCHEMBL3451880 | 0.79 | ITGB3 (0.72) | ITGB3ITGA2BFFAR1RXRBRXRA | |
| SCHEMBL7305023 | 0.78 | ITGB3 (0.71) | ITGB3ITGA2BFFAR1RXRBRXRA | |
| SCHEMBL4622244 | 0.78 | ITGB3 (0.68) | ITGB3ITGA2BFFAR1RXRBRXRA | |
| SCHEMBL7305638 | 0.77 | ITGB3 (0.55) | ITGB3ITGA2BNPC1RAB9A | |
| SCHEMBL4623073 | 0.77 | ITGB3 (0.74) | ITGB3ITGA2BFFAR1RXRBRXRA | |
| SCHEMBL3450818 | 0.76 | ITGB3 (0.72) | ITGB3ITGA2BFFAR1RXRBRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |