Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.81 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.81 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 4/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.49 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.49 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300961 | 0.94 | ITGB3 (0.92) | ITGB3ITGA2BRXRBF2PRSS1 | |
| SCHEMBL7305927 | 0.87 | ITGB3 (0.63) | ITGB3ITGA2BRXRBF2PRSS1 | |
| SCHEMBL7300901 | 0.87 | ITGB3 (0.61) | ITGB3ITGA2BRXRB | |
| SCHEMBL7307011 | 0.87 | ITGB3 (0.62) | ITGB3ITGA2BRXRB | |
| SCHEMBL7307064 | 0.83 | ITGB3 (0.74) | ITGB3ITGA2BRXRBF2PRSS1 | |
| SCHEMBL7305023 | 0.81 | ITGB3 (0.71) | ITGB3ITGA2BRXRB | |
| SCHEMBL7303640 | 0.81 | ITGB3 (0.70) | ITGB3ITGA2BRXRB | |
| SCHEMBL7305419 | 0.79 | ITGB3 (0.74) | ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL7307229 | 0.78 | ITGB3 (0.60) | ITGB3ITGA2BRXRB | |
| SCHEMBL7298489 | 0.77 | ITGB3 (1.00) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |