Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14972591 | 0.85 | MEN1 (0.66) | NPC1RAB9ASMN1; SMN2HDAC3MEN1 | |
| SCHEMBL11195964 | 0.84 | MEN1 (0.59) | TRPV1NPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL7302228 | 0.83 | RAB9A (0.69) | TRPV1NPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL23352871 | 0.82 | TRPV1 (0.68) | TRPV1NPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL6814178 | 0.82 | KCNQ3 (0.60) | NPC1RAB9ASMN1; SMN2HDAC6MEN1 | |
| SCHEMBL27474740 | 0.82 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2HDAC3KCNK9 | |
| SCHEMBL7916064 | 0.82 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2HDAC3HDAC6 | |
| SCHEMBL16097358 | 0.80 | NPC1 (0.61) | TRPV1NPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL1251524 | 0.79 | HDAC6 (0.65) | TRPV1NPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL4191155 | 0.79 | GAA (0.62) | NPC1RAB9ASMN1; SMN2KMT2AKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |