Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294922 | 0.87 | NPC1 (0.71) | RAB9ANPC1SMN1; SMN2TRPV1MAPT | |
| SCHEMBL2679067 | 0.85 | NPC1 (0.73) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL7295519 | 0.84 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2TRPV1MAPT | |
| SCHEMBL7300937 | 0.83 | TRPV1 (0.60) | RAB9ANPC1SMN1; SMN2TRPV1MAPT | |
| SCHEMBL23352871 | 0.82 | TRPV1 (0.68) | RAB9ANPC1SMN1; SMN2TRPV1MAPT | |
| SCHEMBL94560 | 0.82 | NPC1 (0.73) | RAB9ANPC1HTTMAPTNPSR1 | |
| SCHEMBL7303572 | 0.82 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2TRPV1NPSR1 | |
| SCHEMBL21146242 | 0.81 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL4725605 | 0.80 | NPC1 (0.83) | RAB9ANPC1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL19157142 | 0.80 | NPC1 (0.65) | RAB9ANPC1SMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |