SCHEMBL7300962

SCHEMBL7300962

CCCCOC(=O)NC(Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 7/20 0.41
ITGA2B P08514 7/20 0.41
HRH3 Q9Y5N1 9/20 0.40
HRH4 Q9H3N8 4/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ACE P12821 1/20 0.39
ACE2 Q9BYF1 1/20 0.39
ITGB1 P05556 1/20 0.39
ITGA4 P13612 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7300949 1.00 ITGB3 (0.41) ITGB3ITGA2BHRH3HRH4L3MBTL1
SCHEMBL7330192 0.90 ITGB3 (0.41) ITGB3ITGA2BACEACE2ITGB1
SCHEMBL3862102 0.87 ITGB3 (0.40) ITGB3ITGA2BMAPK1SMN1; SMN2
SCHEMBL3862108 0.87 ITGB3 (0.40) ITGB3ITGA2BMAPK1SMN1; SMN2
SCHEMBL14135398 0.85 ITGB3 (0.38) ITGB3ITGA2BHRH3
SCHEMBL4652297 0.83 ITGB3 (0.45) ITGB3ITGA2B
SCHEMBL4653394 0.83 ITGB3 (0.45) ITGB3ITGA2B
SCHEMBL4654556 0.83 ITGB3 (0.45) ITGB3ITGA2B
SCHEMBL753950 0.83 ITGA4 (0.41) ITGB3ITGA2BACEITGA4
SCHEMBL13396568 0.83 ITGB3 (0.37) ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082565-A Self-assembled oxidation mimic enzyme material and preparation method and application thereof 北京化工大学 2023-05-09 CN claimed
CN-116082565-A Self-assembled oxidation mimic enzyme material and preparation method and application thereof 北京化工大学 2023-05-09 CN disclosed
CN-108164506-A A kind of DPP-4 enzyme inhibitors and its preparation and application 上海交通大学 2018-06-15 CN disclosed
EP-0729472-A4 PIPERIDINYLCAMPHORSULFONYL OXYTOCIN ANTAGONISTS MERCK & CO INC (US) 1997-03-19 EP disclosed
EP-0729472-A1 PIPERIDINYLCAMPHORSULFONYL OXYTOCIN ANTAGONISTS MERCK & CO. INC. (US) 1996-09-04 EP disclosed
WO-1995014025-A1 PIPERIDINYLCAMPHORSULFONYL OXYTOCIN ANTAGONISTS MERCK & CO., INC. (US) 1995-05-26 WO disclosed
EP-0486280-A2 Piperidinylcamphorsulfonyl oxytocin antagonists MERCK & CO. INC. (US) 1992-05-20 EP disclosed