Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.71 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2605538 | 0.91 | KCNMA1 (0.71) | KCNMA1HSD17B2HDAC1NPC1RAB9A | |
| SCHEMBL6029542 | 0.91 | KCNMA1 (0.84) | KCNMA1HDAC1NPC1RAB9AALDH1A1 | |
| SCHEMBL2605548 | 0.89 | KCNMA1 (0.82) | KCNMA1HDAC1NPC1RAB9AALDH1A1 | |
| SCHEMBL7292413 | 0.88 | HSD17B2 (0.58) | KCNMA1HSD17B2NR1H4KCNK3NPC1 | |
| SCHEMBL6030714 | 0.87 | KCNMA1 (0.56) | KCNMA1NR1H4HDAC1NPC1RAB9A | |
| SCHEMBL7304022 | 0.86 | HTT (0.67) | KCNMA1NR1H4HDAC1KCNK3NPC1 | |
| SCHEMBL12937567 | 0.86 | KCNMA1 (0.68) | KCNMA1HDAC1NPC1RAB9ATP53 | |
| SCHEMBL14363236 | 0.86 | KCNMA1 (0.77) | KCNMA1HDAC1NPC1RAB9AALDH1A1 | |
| SCHEMBL2605545 | 0.85 | KCNMA1 (0.62) | KCNMA1HDAC1NPC1RAB9AALDH1A1 | |
| SCHEMBL2605537 | 0.84 | KCNMA1 (0.70) | KCNMA1HDAC1NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |