Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13518976 | 0.85 | LMNA (0.56) | S1PR1FFAR1S1PR3KMT2ACYP2D6 | |
| SCHEMBL28530456 | 0.79 | LMNA (0.53) | FFAR1KMT2AALDH1A1HPGDCYP2D6 | |
| SCHEMBL2004125 | 0.78 | SLC1A2 (0.67) | KMT2AALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2004120 | 0.78 | SLC1A2 (0.67) | KMT2AALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22281732 | 0.78 | IDO1 (0.48) | FAAH | |
| SCHEMBL15707944 | 0.78 | SLC1A3 (0.51) | FFAR1KMT2AALDH1A1HPGDCYP2D6 | |
| SCHEMBL22861338 | 0.76 | TDP1 (0.49) | — | |
| SCHEMBL9205158 | 0.76 | TDP1 (0.49) | — | |
| SCHEMBL15869589 | 0.76 | FFAR1 (0.56) | S1PR1FFAR1S1PR3S1PR5KMT2A | |
| SCHEMBL7302270 | 0.74 | PPARG (0.48) | FFAR1KMT2AALDH1A1HPGDCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |