Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9725902 | 0.99 | GRIN2B (0.49) | ALDH1A1GRIN2BMAPK1L3MBTL1SIGMAR1 | |
| SCHEMBL4634622 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1GAATSHR | |
| SCHEMBL18154137 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1GAALMNA | |
| SCHEMBL22416691 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MAPK1L3MBTL1GAA | |
| SCHEMBL1414262 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MAPK1L3MBTL1GAA | |
| SCHEMBL7334700 | 0.82 | MTNR1A (0.47) | ALDH1A1GRIN2BGAA | |
| Hydrochloric Acid SCHEMBL1414261 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1GAALMNA | |
| SCHEMBL15521641 | 0.81 | KEAP1 (0.48) | ALDH1A1MAPK1L3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL7334726 | 0.81 | MTNR1A (0.46) | ALDH1A1GRIN2BGAA | |
| SCHEMBL24188907 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014202659-A1 | PROCESS FOR THE PREPARATION OF AMIDES OF N-[1-(S)-(ETHOXYCARBONYL)-3-PHENYLPROPYL]-L-ALANINE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2014-12-24 | — | — | WO | disclosed |
| EP-0494071-B1 | Trifluoromethylketone tripeptide derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-04-16 | — | — | EP | disclosed |
| US-5430025-A | Elastase-inhibiting peptides bearing a C-terminal trifluoromethylketone moiety | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| US-5296591-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0281393-B1 | METHOD FOR PRODUCING INDAN DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1993-08-04 | — | — | EP | disclosed |
| EP-0494071-A2 | Trifluoromethylketone tripeptide derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-5098892-A | Angiotensin converting enzyme inhibitors as hypotensive agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| US-4835302-A | Method for producing indan derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-30 | — | — | US | disclosed |
| US-4831184-A | N-substituted-amido-amino acids | RORER PHARMACEUTICAL CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |
| US-4822818-A | ANTIHYPERTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0281393-A2 | Method for producing indan derivatives | Takeda Chemical Industries, Ltd. (JP) | 1988-09-07 | — | — | EP | disclosed |
| US-4474692-A | L-Alanyl-N-(indan-2-yl)glycine, its esters and salts thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-10-02 | — | — | US | disclosed |
| EP-0051391-B1 | BICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-09-05 | — | — | EP | disclosed |
| EP-0051391-A1 | Bicyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-05-12 | — | — | EP | disclosed |