Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.60 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.42 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301514 | 0.91 | ITGB3 (0.62) | ITGB3ITGA2BCYP51A1CA2KMT2A | |
| SCHEMBL7291927 | 0.88 | ITGB3 (0.62) | ITGB3ITGA2BCYP51A1CA2KMT2A | |
| SCHEMBL7291943 | 0.87 | ITGB3 (0.61) | ITGB3ITGA2BCYP51A1CA2KMT2A | |
| SCHEMBL8643931 | 0.86 | ITGB3 (0.55) | ITGB3ITGA2B | |
| SCHEMBL7292028 | 0.86 | ITGB3 (0.82) | ITGB3ITGA2BCYP51A1CA2F2 | |
| SCHEMBL7284349 | 0.86 | ITGB3 (0.82) | ITGB3ITGA2BCYP51A1CA2F2 | |
| SCHEMBL9259158 | 0.83 | ITGB3 (0.60) | ITGB3ITGA2BCYP51A1CA2KMT2A | |
| SCHEMBL8020868 | 0.81 | ITGB3 (0.75) | ITGB3ITGA2BCYP51A1F2PLG | |
| SCHEMBL8689958 | 0.78 | ITGB3 (0.73) | ITGB3ITGA2BCYP51A1F2PLG | |
| SCHEMBL7302621 | 0.78 | ITGB3 (0.53) | ITGB3ITGA2BCYP51A1CA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505868-B1 | N-Acyl-alpha-aminoacids derivatives | HOFFMANN LA ROCHE (CH) | 1995-09-13 | — | — | EP | claimed |