Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.62 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301509 | 0.91 | ITGB3 (0.60) | ITGB3ITGA2BCYP51A1KMT2ACA2 | |
| SCHEMBL8020868 | 0.91 | ITGB3 (0.75) | ITGB3ITGA2BCYP51A1F2PLG | |
| SCHEMBL7291927 | 0.89 | ITGB3 (0.62) | ITGB3ITGA2BCYP51A1KMT2ACA2 | |
| SCHEMBL7291943 | 0.89 | ITGB3 (0.61) | ITGB3ITGA2BCYP51A1KMT2ACA2 | |
| SCHEMBL7292028 | 0.87 | ITGB3 (0.82) | ITGB3ITGA2BCYP51A1CA2F2 | |
| SCHEMBL7284349 | 0.87 | ITGB3 (0.82) | ITGB3ITGA2BCYP51A1CA2F2 | |
| SCHEMBL9259158 | 0.85 | ITGB3 (0.60) | ITGB3ITGA2BCYP51A1KMT2ACA2 | |
| SCHEMBL8690536 | 0.84 | ITGB3 (0.55) | ITGB3ITGA2BF2PLGPOLB | |
| SCHEMBL8689958 | 0.83 | ITGB3 (0.73) | ITGB3ITGA2BCYP51A1F2PLG | |
| SCHEMBL27386352 | 0.81 | ITGB3 (0.61) | ITGB3ITGA2BCYP51A1CA2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505868-B1 | N-Acyl-alpha-aminoacids derivatives | HOFFMANN LA ROCHE (CH) | 1995-09-13 | — | — | EP | claimed |