Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304406 | 0.74 | LMNA (0.38) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL7296987 | 0.73 | LMNA (0.45) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL18362302 | 0.67 | GPR119 (0.36) | AR | |
| Hydrochloric Acid SCHEMBL7292225 | 0.66 | LMNA (0.44) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL24081325 | 0.61 | LMNA (0.55) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL29378876 | 0.61 | LMNA (0.55) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL10076829 | 0.61 | LMNA (0.55) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL10076833 | 0.61 | LMNA (0.55) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL639674 | 0.60 | CHRM2 (0.52) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL17062522 | 0.60 | CHRM2 (0.52) | LMNACYP2C9CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252570-A | Amidino and guanidino derivatives | B.I. ITALIA (IT) | 1993-10-12 | — | — | US | disclosed |
| US-5047410-A | Indolyl derivatives and their use as 5-HT3, receptor antagonists | ISTITUTO DE ANGELI S.P.A. (IT) | 1991-09-10 | — | — | US | disclosed |
| EP-0351385-A2 | New amidino and guanidino derivatives | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1990-01-17 | — | — | EP | disclosed |