Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301554 | 0.74 | LMNA (0.38) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL7302587 | 0.72 | GPR119 (0.39) | — | |
| SCHEMBL17992450 | 0.70 | DPP4 (0.33) | — | |
| SCHEMBL10713252 | 0.66 | — | — | |
| SCHEMBL18781207 | 0.64 | LMNA (0.35) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL18867642 | 0.64 | KDM4E (0.31) | — | |
| SCHEMBL18780989 | 0.64 | LMNA (0.35) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL2632043 | 0.63 | KDM4E (0.39) | — | |
| SCHEMBL17992445 | 0.63 | KDM4E (0.39) | — | |
| SCHEMBL18867784 | 0.62 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252570-A | Amidino and guanidino derivatives | B.I. ITALIA (IT) | 1993-10-12 | — | — | US | disclosed |
| US-5047410-A | Indolyl derivatives and their use as 5-HT3, receptor antagonists | ISTITUTO DE ANGELI S.P.A. (IT) | 1991-09-10 | — | — | US | disclosed |
| EP-0351385-A2 | New amidino and guanidino derivatives | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1990-01-17 | — | — | EP | disclosed |