Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | GPR139 | Q6DWJ6 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310513 | 0.86 | KDM4E (0.40) | GPR139GAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7313887 | 0.85 | CYP2C19 (0.46) | CYP2C19GPR139POLBCYP2C9HTT | |
| SCHEMBL6474360 | 0.83 | CYP2C19 (0.50) | CYP2C19GPR139POLBCYP2C9HTT | |
| SCHEMBL6474544 | 0.76 | CYP2C19 (0.47) | CYP2C19GPR139POLBCYP2C9HTT | |
| SCHEMBL7303747 | 0.73 | TNF (0.38) | CYP2C19GPR139CYP2C9GAAKDM4E | |
| SCHEMBL11469517 | 0.70 | CYP2C19 (0.52) | CYP2C19GPR139POLBCYP2C9HTT | |
| SCHEMBL6474507 | 0.70 | KDM4E (0.41) | GAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL17141321 | 0.69 | GPR139 (0.58) | GPR139HTTMEN1KMT2AGAA | |
| SCHEMBL253984 | 0.67 | SCN5A (0.60) | GPR139 | |
| SCHEMBL4492226 | 0.65 | ALDH1A1 (0.54) | CYP2C19POLBCYP2C9HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854140-B1 | Vitronectin receptor antagonists, their production and their use | SANOFI AVENTIS DEUTSCHLAND (DE) | 2013-11-06 | — | — | EP | disclosed |
| EP-0854140-A2 | Vitronectin receptor antagonists, their production and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-22 | — | — | EP | disclosed |