Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.67 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.67 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696113 | 1.00 | ENPP1 (0.67) | ENPP1ENPP3TRPV1MEN1KMT2A | |
| SCHEMBL7303163 | 0.83 | HDAC3 (0.86) | TRPV1MEN1KMT2ACA1CA2 | |
| SCHEMBL7301192 | 0.82 | NPC1 (0.81) | TRPV1MEN1KMT2AHDAC3HDAC11 | |
| SCHEMBL7304276 | 0.82 | NPC1 (0.81) | TRPV1MEN1KMT2AHDAC3HDAC11 | |
| SCHEMBL2990592 | 0.81 | CA1 (0.68) | ENPP1ENPP3MEN1KMT2ACA1 | |
| SCHEMBL7294862 | 0.79 | TRPV1 (0.68) | TRPV1MEN1KMT2AHDAC3HDAC11 | |
| SCHEMBL7302201 | 0.78 | NPC1 (0.74) | TRPV1MEN1KMT2AHDAC3HDAC11 | |
| SCHEMBL30994893 | 0.78 | PGR (0.74) | TRPV1MEN1KMT2AHDAC3HDAC11 | |
| SCHEMBL557111 | 0.77 | HDAC6 (0.71) | ENPP1TRPV1MEN1KMT2ACA1 | |
| SCHEMBL3882727 | 0.77 | HDAC3 (0.71) | TRPV1MEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |