Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 6/20 | 0.44 |
| ▸ | CASP1 | P29466 | 5/20 | 0.42 |
| ▸ | CASP7 | P55210 | 5/20 | 0.42 |
| ▸ | CASP6 | P55212 | 5/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 5/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.39 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.39 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301631 | 1.00 | ALDH1A1 (0.48) | ALDH1A1HPGDUSP2POLBMAPT | |
| SCHEMBL7303797 | 0.92 | ALDH1A1 (0.49) | ALDH1A1HPGDUSP2POLBMAPT | |
| SCHEMBL7311200 | 0.92 | ALDH1A1 (0.49) | ALDH1A1HPGDUSP2POLBMAPT | |
| SCHEMBL7311213 | 0.92 | ALDH1A1 (0.49) | ALDH1A1HPGDUSP2POLBMAPT | |
| SCHEMBL7303784 | 0.92 | ALDH1A1 (0.49) | ALDH1A1HPGDUSP2POLBMAPT | |
| SCHEMBL7341599 | 0.91 | ALDH1A1 (0.56) | ALDH1A1HPGDUSP2POLBMAPT | |
| SCHEMBL7302463 | 0.90 | ALDH1A1 (0.48) | ALDH1A1HPGDUSP2POLBMAPT | |
| SCHEMBL7302479 | 0.90 | ALDH1A1 (0.48) | ALDH1A1HPGDUSP2POLBMAPT | |
| SCHEMBL7315656 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HPGDUSP2POLBMAPT | |
| SCHEMBL7315644 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HPGDUSP2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525420-B1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | MITSUBISHI CHEM CORP (JP) | 1999-05-12 | — | — | EP | disclosed |
| US-5834508-A | PROTEASE ENZYME INHIBITORS; MUSCLE DISORDERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0525420-A1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | Mitsubishi Chemical Corporation (JP) | 1993-02-03 | — | — | EP | disclosed |