Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 7/20 | 0.46 |
| ▸ | CASP1 | P29466 | 6/20 | 0.44 |
| ▸ | CASP7 | P55210 | 6/20 | 0.44 |
| ▸ | CASP6 | P55212 | 6/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTRA1 | Q92743 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315644 | 1.00 | ALDH1A1 (0.51) | ALDH1A1POLBMAPTUSP2HPGD | |
| SCHEMBL7311213 | 0.88 | ALDH1A1 (0.49) | ALDH1A1POLBMAPTUSP2HPGD | |
| SCHEMBL7303784 | 0.88 | ALDH1A1 (0.49) | ALDH1A1POLBMAPTUSP2HPGD | |
| SCHEMBL7303797 | 0.88 | ALDH1A1 (0.49) | ALDH1A1POLBMAPTUSP2HPGD | |
| SCHEMBL7311200 | 0.88 | ALDH1A1 (0.49) | ALDH1A1POLBMAPTUSP2HPGD | |
| SCHEMBL7302479 | 0.86 | ALDH1A1 (0.48) | ALDH1A1POLBMAPTUSP2HPGD | |
| SCHEMBL7302463 | 0.86 | ALDH1A1 (0.48) | ALDH1A1POLBMAPTUSP2HPGD | |
| SCHEMBL7301641 | 0.86 | ALDH1A1 (0.48) | ALDH1A1POLBMAPTUSP2HPGD | |
| SCHEMBL7301631 | 0.86 | ALDH1A1 (0.48) | ALDH1A1POLBMAPTUSP2HPGD | |
| SCHEMBL7444208 | 0.84 | ALDH1A1 (0.46) | ALDH1A1POLBMAPTUSP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525420-B1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | MITSUBISHI CHEM CORP (JP) | 1999-05-12 | — | — | EP | disclosed |
| US-5834508-A | PROTEASE ENZYME INHIBITORS; MUSCLE DISORDERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0525420-A1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | Mitsubishi Chemical Corporation (JP) | 1993-02-03 | — | — | EP | disclosed |