Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 11/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454214 | 0.85 | NOTUM (0.64) | NOTUMMEN1KMT2APTGES | |
| SCHEMBL24548630 | 0.80 | NOTUM (0.50) | NOTUMMEN1KMT2A | |
| SCHEMBL6748172 | 0.78 | BRD4 (0.56) | NOTUMMAOB | |
| SCHEMBL29717244 | 0.76 | NOTUM (0.49) | NOTUMMEN1KMT2APTGES | |
| SCHEMBL29147534 | 0.76 | LTA4H (0.47) | MAOB | |
| SCHEMBL189126 | 0.75 | PSMB8 (0.63) | MEN1KMT2AGSTP1MAOB | |
| SCHEMBL2492377 | 0.74 | NOTUM (0.46) | NOTUM | |
| SCHEMBL29147860 | 0.74 | NPC1 (0.51) | MAOB | |
| SCHEMBL29125684 | 0.73 | ALDH1A1 (0.48) | NOTUMMEN1KMT2A | |
| SCHEMBL7298311 | 0.73 | NOTUM (0.63) | NOTUMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655445-B1 | 1,3,4-oxadiazol-2(3H)-one Derivates, their preparation and their use as monoamine oxidase inhibitors | SYNTHELABO (FR) | 1997-08-27 | — | — | EP | disclosed |
| US-5525619-A | INHIBITORS OF MONOAMINE OXIDASE B | SYNTHELABO (FR) | 1996-06-11 | — | — | US | disclosed |
| EP-0655445-A1 | 1,3,4-oxadiazol-2(3H)-one Derivates, their preparation and their use as monoamine oxidase inhibitors | SYNTHELABO (FR) | 1995-05-31 | — | — | EP | disclosed |