SCHEMBL7301853

SCHEMBL7301853

CC(C)C[C@H](N)C(=O)NN1CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.46
ANPEP P15144 2/20 0.44
RNPEP Q9H4A4 2/20 0.44
DNPEP Q9ULA0 1/20 0.44
SLC7A5 Q01650 1/20 0.42
LARS1 Q9P2J5 3/20 0.41
MMP1 P03956 2/20 0.41
MMP2 P08253 2/20 0.41
MMP8 P22894 2/20 0.41
DPP7 Q9UHL4 3/20 0.40
DPP4 P27487 1/20 0.40
DPP8 Q6V1X1 1/20 0.40
DPP9 Q86TI2 1/20 0.40
AAK1 Q2M2I8 1/20 0.36
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
HTT P42858 1/20 0.34
MMP3 P08254 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8130404 0.98 ANPEP (0.45) L3MBTL1ANPEPRNPEPDNPEPSLC7A5
SCHEMBL22530895 0.79 PTGS1 (0.39) L3MBTL1ANPEPMMP2DPP7HTT
SCHEMBL28682071 0.77 L3MBTL1 (0.42) L3MBTL1DPP7DPP4DPP8DPP9
SCHEMBL8869669 0.77 L3MBTL1 (0.42) L3MBTL1DPP7DPP4DPP8DPP9
SCHEMBL7301848 0.77 MMP1 (0.46) ANPEPRNPEPDNPEPSLC7A5LARS1
Hydrochloric Acid SCHEMBL11112714 0.76 L3MBTL1 (0.37) L3MBTL1DPP7HTT
SCHEMBL21650439 0.75 L3MBTL1 (0.47) L3MBTL1HTT
SCHEMBL3703881 0.75 DPP4 (0.43) L3MBTL1DPP7DPP4DPP8DPP9
SCHEMBL11115955 0.75 L3MBTL1 (0.36) L3MBTL1DPP7HTT
SCHEMBL17152580 0.74 NPC1 (0.47) MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5214056-A Thiol protease inhibitors JAPAN TOBACCO INC. (JP) 1993-05-25 US disclosed
EP-0460239-A1 1,3,2-DIOXATHIOLANE OXIDE DERIVATIVE Japan Tobacco Inc. (JP) 1991-12-11 EP disclosed