Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.45 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.45 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | LARS1 | Q9P2J5 | 4/20 | 0.42 |
| ▸ | DPP4 | P27487 | 4/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301853 | 0.98 | L3MBTL1 (0.46) | ANPEPRNPEPDNPEPL3MBTL1SLC7A5 | |
| SCHEMBL8869669 | 0.79 | L3MBTL1 (0.42) | L3MBTL1DPP4DPP7DPP8DPP9 | |
| SCHEMBL28682071 | 0.79 | L3MBTL1 (0.42) | L3MBTL1DPP4DPP7DPP8DPP9 | |
| SCHEMBL22530895 | 0.76 | PTGS1 (0.39) | ANPEPL3MBTL1DPP7MMP2 | |
| SCHEMBL11115955 | 0.76 | L3MBTL1 (0.36) | L3MBTL1DPP7 | |
| SCHEMBL9684035 | 0.75 | L3MBTL1 (0.39) | L3MBTL1DPP4DPP7DPP8DPP9 | |
| SCHEMBL7301848 | 0.75 | MMP1 (0.46) | ANPEPRNPEPDNPEPSLC7A5LARS1 | |
| Hydrochloric Acid SCHEMBL11109067 | 0.75 | L3MBTL1 (0.35) | L3MBTL1DPP7 | |
| SCHEMBL10305720 | 0.74 | L3MBTL1 (0.44) | L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11112714 | 0.73 | L3MBTL1 (0.37) | L3MBTL1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543858-B1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND APPLICATION | BRITISH BIOTECH PHARM (GB) | 2000-12-20 | — | — | EP | disclosed |
| US-5451676-A | Treatment of hypotension and bronchoconstriction | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-09-19 | — | — | US | disclosed |
| US-5274094-A | Diseases or conditions mediated by platelet-activating factor; cyclization of a diamino compound with a carboxylic acid | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-12-28 | — | — | US | disclosed |
| EP-0543858-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND APPLICATION | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| US-5200412-A | Antiinflammatory agents and antiallergens | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-04-06 | — | — | US | disclosed |
| WO-1992003423-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |