Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554834 | 0.77 | REN (0.32) | RENBACE1 | |
| SCHEMBL9554839 | 0.77 | REN (0.32) | RENBACE1 | |
| Hydrochloric Acid SCHEMBL10477780 | 0.74 | REN (0.40) | REN | |
| Hydrochloric Acid SCHEMBL10477793 | 0.74 | REN (0.33) | RENBACE1 | |
| SCHEMBL10825161 | 0.73 | BACE1 (0.41) | RENBACE1 | |
| SCHEMBL10825121 | 0.73 | BACE1 (0.41) | RENBACE1 | |
| SCHEMBL10825117 | 0.73 | BACE1 (0.41) | RENBACE1 | |
| SCHEMBL29473464 | 0.72 | REN (0.43) | REN | |
| Hydrochloric Acid SCHEMBL10477741 | 0.72 | IL1RN (0.34) | REN | |
| Hydrochloric Acid SCHEMBL10477681 | 0.72 | IL1RN (0.34) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990002137-A1 | RENIN INHIBITORY PEPTIDES CONTAINING SULEPTANIC ACID OR DERIVATIVES THEREOF | THE UPJOHN COMPANY (US) | 1990-03-08 | — | — | WO | claimed |
| EP-0355065-A1 | Renin inhibitory peptides containing suleptanic acid or derivatives thereof | THE UPJOHN COMPANY (US) | 1990-02-21 | — | — | EP | claimed |
| WO-1990002137-A1 | RENIN INHIBITORY PEPTIDES CONTAINING SULEPTANIC ACID OR DERIVATIVES THEREOF | THE UPJOHN COMPANY (US) | 1990-03-08 | — | — | WO | disclosed |
| EP-0355065-A1 | Renin inhibitory peptides containing suleptanic acid or derivatives thereof | THE UPJOHN COMPANY (US) | 1990-02-21 | — | — | EP | disclosed |