Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | ACACB | O00763 | 11/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211504 | 0.86 | GPR119 (0.55) | POLBGAAGPR119 | |
| SCHEMBL7341665 | 0.79 | GPR119 (0.45) | GPR119ACACB | |
| SCHEMBL3724395 | 0.77 | GPR119 (0.46) | GPR119ACACB | |
| SCHEMBL373517 | 0.77 | GPR119 (0.46) | GPR119ACACB | |
| SCHEMBL7308360 | 0.74 | GPR119 (0.44) | GPR119ACACB | |
| SCHEMBL14795178 | 0.74 | ACACB (0.49) | GPR119ACACB | |
| SCHEMBL373589 | 0.73 | MAPT (0.42) | GPR119 | |
| SCHEMBL7166722 | 0.69 | POLB (0.82) | POLBGAA | |
| SCHEMBL3296454 | 0.68 | POLB (0.55) | POLBGAA | |
| SCHEMBL187570 | 0.68 | ACKR3 (0.40) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938489-A1 | NEW PHOSPHONATES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS | Roche Diagnostics GmbH (DE) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998022483-A1 | NEW PHOSPHONATES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS | ROCHE DIAGNOSTICS GMBH (DE) | 1998-05-28 | — | — | WO | disclosed |
| EP-0842941-A1 | Novel phosphonates, process for their preparation and pharmaceutical compositions | Roche Diagnostics GmbH (DE) | 1998-05-20 | — | — | EP | disclosed |