Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014736 | 0.89 | FAAH (0.42) | GPR119FAAHEPHX2ACACBKDM4E | |
| SCHEMBL373517 | 0.86 | GPR119 (0.46) | GPR119FAAHEPHX2ACACBHRH3 | |
| SCHEMBL3724395 | 0.86 | GPR119 (0.46) | GPR119ACACBALDH1A1HRH3CHEK2 | |
| SCHEMBL23086694 | 0.83 | FAAH (0.41) | GPR119FAAHEPHX2ACACBKDM4E | |
| SCHEMBL224172 | 0.82 | GPR119 (0.63) | GPR119ALDH1A1HRH3CHEK2USP30 | |
| SCHEMBL14795178 | 0.80 | ACACB (0.49) | GPR119ACACB | |
| SCHEMBL31731237 | 0.80 | GPR119 (0.43) | GPR119FAAHEPHX2HRH3 | |
| SCHEMBL373589 | 0.79 | MAPT (0.42) | GPR119HRH3 | |
| SCHEMBL6190259 | 0.78 | GPR119 (0.55) | GPR119ALDH1A1HRH3CHEK2USP30 | |
| SCHEMBL7389137 | 0.78 | GPR119 (0.55) | GPR119ALDH1A1HRH3CHEK2USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938489-A1 | NEW PHOSPHONATES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS | Roche Diagnostics GmbH (DE) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998022483-A1 | NEW PHOSPHONATES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS | ROCHE DIAGNOSTICS GMBH (DE) | 1998-05-28 | — | — | WO | disclosed |
| EP-0842941-A1 | Novel phosphonates, process for their preparation and pharmaceutical compositions | Roche Diagnostics GmbH (DE) | 1998-05-20 | — | — | EP | disclosed |