Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308762 | 0.85 | QDPR (0.48) | PARP1SIGMAR1DRD2 | |
| SCHEMBL6373460 | 0.76 | PARP1 (0.50) | PPARGPPARAPARP1SIGMAR1HTR7 | |
| SCHEMBL6374865 | 0.72 | PARP1 (0.48) | PPARGPPARAPARP1SIGMAR1HTR7 | |
| SCHEMBL7104174 | 0.71 | PARP1 (0.47) | PPARGPPARAPARP1SIGMAR1DRD2 | |
| SCHEMBL16843071 | 0.70 | SIGMAR1 (0.50) | SIGMAR1DRD2 | |
| SCHEMBL11932475 | 0.70 | SIGMAR1 (0.61) | PPARGPPARAPARP1SIGMAR1HTR7 | |
| SCHEMBL8915112 | 0.69 | QDPR (0.62) | PPARGPPARA | |
| SCHEMBL9967722 | 0.69 | SIGMAR1 (0.56) | SIGMAR1 | |
| SCHEMBL7296334 | 0.67 | PPARG (0.56) | PPARGPPARAPARP1SIGMAR1 | |
| SCHEMBL1470365 | 0.67 | DRD4 (0.52) | PARP1SIGMAR1MAPK1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149817-A | Psychotropic agents | SHIONOGI & CO., LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0445701-A1 | Novel tetrahydropyridine derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |