Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.45 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.45 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9120276 | 0.81 | KCNMA1 (0.55) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL4940897 | 0.79 | ALDH1A1 (0.65) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL29061899 | 0.78 | HSD17B10 (0.53) | MEN1KMT2AKDM4ERAB9AGAA | |
| Ammonia Solution, Strong SCHEMBL27766738 | 0.77 | ALDH1A1 (0.62) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL9120292 | 0.75 | MEN1 (0.65) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL1863070 | 0.75 | KMT2A (1.00) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL7302607 | 0.74 | KDM1A (0.54) | MEN1KMT2AMAPTKDM4ERAB9A | |
| SCHEMBL397773 | 0.74 | MAPK1 (0.77) | MEN1KMT2AMAPTMAPK1RAB9A | |
| SCHEMBL4593816 | 0.74 | CDC25B (0.61) | MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL12527917 | 0.73 | KCNMA1 (0.51) | MEN1KMT2AMAPTKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520200-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1998-02-18 | — | — | EP | disclosed |
| US-5210091-A | Calcium channel blockers used in treatment of central nervous system disorders | NEUROSEARCH A/S (DK) | 1993-05-11 | — | — | US | disclosed |
| EP-0520200-A2 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1992-12-30 | — | — | EP | disclosed |