Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29061899 | 0.84 | HSD17B10 (0.53) | G6PDHCRTR1PTPN22ALDH1A1GAA | |
| SCHEMBL9116508 | 0.79 | GAA (0.55) | G6PDALDH1A1GAAKDM4EMAPT | |
| SCHEMBL7862553 | 0.78 | KDM1A (0.55) | KDM1AMAPK14ALDH1A1GAAKDM4E | |
| SCHEMBL4593816 | 0.76 | CDC25B (0.61) | G6PDKDM4EMEN1KMT2ALMNA | |
| SCHEMBL15382645 | 0.76 | POLB (0.57) | G6PDHCRTR1ALDH1A1GAAKDM4E | |
| SCHEMBL10871261 | 0.75 | G6PD (0.54) | KDM1AG6PDHCRTR1PTPN22ALDH1A1 | |
| SCHEMBL7161381 | 0.75 | MAPT (0.47) | KDM1AMAPK14ALDH1A1GAAKDM4E | |
| SCHEMBL819667 | 0.74 | ALDH1A1 (0.59) | KDM1AMAPK14ALDH1A1GAAKDM4E | |
| SCHEMBL28872379 | 0.74 | PTPN22 (0.54) | G6PDHCRTR1PTPN22ALDH1A1GAA | |
| SCHEMBL7302129 | 0.74 | MEN1 (0.62) | ALDH1A1GAAKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520200-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1998-02-18 | — | — | EP | disclosed |
| US-5210091-A | Calcium channel blockers used in treatment of central nervous system disorders | NEUROSEARCH A/S (DK) | 1993-05-11 | — | — | US | disclosed |
| EP-0520200-A2 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1992-12-30 | — | — | EP | disclosed |