Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.73 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.71 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.69 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.69 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303163 | 0.91 | HDAC3 (0.86) | NPC1RAB9ASMN1; SMN2HDAC3HDAC6 | |
| SCHEMBL28330745 | 0.89 | SMN1; SMN2 (0.78) | NPC1RAB9ASMN1; SMN2HDAC3HDAC6 | |
| SCHEMBL611657 | 0.87 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL10939703 | 0.87 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL9767723 | 0.87 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL5226687 | 0.86 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2NR1H4 | |
| SCHEMBL13945764 | 0.85 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2HDAC3HDAC6 | |
| SCHEMBL1291198 | 0.85 | RAB9A (0.73) | NPC1RAB9ASMN1; SMN2HDAC3HDAC6 | |
| SCHEMBL4627548 | 0.85 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2HDAC3HDAC6 | |
| SCHEMBL7296645 | 0.84 | HDAC3 (0.75) | NPC1RAB9ASMN1; SMN2HDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-01-28 | — | — | US | disclosed |
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | ME1, MAL2, ME3 | NPC1 4630/4885RAB9A 4007/4885SMN1; SMN2 1799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.