Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 2/20 | 0.49 |
| ▸ | CPB1 | P15086 | 1/20 | 0.49 |
| ▸ | CPA3 | P15088 | 1/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278126 | 0.84 | ALDH1A1 (0.62) | L3MBTL1HPGDALDH1A1LMNAGAA | |
| SCHEMBL7280357 | 0.83 | LMNA (0.51) | L3MBTL1HPGDALDH1A1KMT2ALMNA | |
| SCHEMBL9554486 | 0.78 | CPA1 (0.60) | KMT2ALMNACPA1CPB1CPA3 | |
| SCHEMBL9554490 | 0.78 | CPA1 (0.60) | KMT2ALMNACPA1CPB1CPA3 | |
| SCHEMBL7280897 | 0.78 | SMN1; SMN2 (0.61) | L3MBTL1HPGDALDH1A1KMT2ALMNA | |
| SCHEMBL7346172 | 0.78 | CYP1A2 (0.77) | ALDH1A1ANPEPERAP2ERAP1CPA1 | |
| SCHEMBL2804430 | 0.77 | CPA1 (0.63) | LMNACPA1CPB1CPA3CPB2 | |
| SCHEMBL7298841 | 0.76 | KMT2A (0.48) | KDM4EHPGDALDH1A1KMT2ALMNA | |
| SCHEMBL7280848 | 0.75 | LMNA (0.63) | KDM4EHPGDALDH1A1KMT2ALMNA | |
| SCHEMBL7295898 | 0.75 | KMT2A (0.58) | KDM4EHPGDALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063208-A | Cardiovascular disorders, vision defects | ABBOTT LABORATORIES (US) | 1991-11-05 | — | — | US | disclosed |
| EP-0410260-A2 | Peptidyl aminodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-01-30 | — | — | EP | disclosed |