Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 13/20 | 0.48 |
| ▸ | PREP | P48147 | 5/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302790 | 0.87 | PREP (0.51) | FKBP1APREPACERAB9A | |
| SCHEMBL6883743 | 0.81 | FKBP1A (0.49) | FKBP1AACEACE2 | |
| SCHEMBL5497995 | 0.81 | FKBP1A (0.49) | FKBP1AACEACE2 | |
| SCHEMBL5497998 | 0.81 | FKBP1A (0.49) | FKBP1AACEACE2 | |
| SCHEMBL7304041 | 0.80 | PREP (0.51) | PREPACEHPGD | |
| SCHEMBL7296448 | 0.80 | PREP (0.69) | PREP | |
| SCHEMBL7305993 | 0.79 | CHRM2 (0.56) | PREPACEACE2 | |
| SCHEMBL7294720 | 0.78 | CHRM2 (0.55) | PREPACEACE2 | |
| SCHEMBL7295390 | 0.77 | PREP (0.64) | FKBP1APREPHPGD | |
| SCHEMBL7293607 | 0.76 | PREP (0.54) | PREPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |