Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28382023 | 0.82 | RIPK1 (0.35) | TAAR1 | |
| SCHEMBL536253 | 0.82 | ESR1 (0.41) | TAAR1ESR1ESR2AOC3 | |
| SCHEMBL28378978 | 0.79 | RIPK1 (0.33) | TAAR1 | |
| SCHEMBL25334 | 0.78 | ALDH1A1 (0.40) | TAAR1 | |
| SCHEMBL2448821 | 0.76 | TRPA1 (0.38) | TAAR1ESR1ESR2AOC3 | |
| SCHEMBL1029392 | 0.76 | AOC3 (0.34) | TAAR1ESR1ESR2AOC3 | |
| SCHEMBL1028273 | 0.76 | AOC3 (0.34) | TAAR1ESR1ESR2AOC3 | |
| SCHEMBL23983 | 0.76 | AOC3 (0.34) | TAAR1ESR1ESR2AOC3 | |
| SCHEMBL3649949 | 0.76 | TRPA1 (0.42) | TAAR1ESR1ESR2AOC3 | |
| SCHEMBL6487836 | 0.76 | TAAR1 (0.33) | TAAR1ESR1ESR2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011124-B | Production method of trisphenol compound | 常州市天华制药有限公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-1196056-A | Cyclic Worm Inhibitors | UPJOHN CO (US) | 1998-10-14 | — | — | CN | disclosed |
| CN-1026063-C | Pharmaceutical composition containing substituted thiopheno derivatives | HOECHST AG (DE) | 1994-10-05 | — | — | CN | disclosed |
| CN-1021911-C | Process for the preparation of substituted thienoimidazole derivatives | HOECHST AG (DE) | 1993-08-25 | — | — | CN | disclosed |
| EP-0546115-A1 | PEPTIDES CONTAINING AMINO-POLYOLS AS TRANSITION-STATE MIMICS | THE UPJOHN COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992003472-A1 | PEPTIDES CONTAINING AMINO-POLYOLS AS TRANSITION-STATE MIMICS | THE UPJOHN COMPANY (US) | 1992-03-05 | — | — | WO | disclosed |
| CN-1049163-A | The pharmaceutical composition that contains the thiopheno derivatives of replacement | HOECHST AG (DE) | 1991-02-13 | — | — | CN | disclosed |
| EP-0355065-A1 | Renin inhibitory peptides containing suleptanic acid or derivatives thereof | THE UPJOHN COMPANY (US) | 1990-02-21 | — | — | EP | disclosed |
| CN-87100719-A | Substituted thieno derivatives, process for their preparation, pharmaceutical compositions containing them and their use as gastric acid secretion inhibitors | — | 1987-09-09 | — | — | CN | disclosed |