Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.69 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8384991 | 0.88 | ITGB3 (0.70) | ITGB3ITGA2B | |
| SCHEMBL7304632 | 0.84 | ITGB3 (0.57) | ITGB3ITGA2BKDM4EHTTNPC1 | |
| SCHEMBL7297075 | 0.81 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL7307903 | 0.79 | ITGB3 (0.57) | ITGB3ITGA2B | |
| SCHEMBL8384078 | 0.77 | ITGB3 (0.56) | ITGB3ITGA2BKDM4E | |
| SCHEMBL7330638 | 0.76 | ITGB3 (0.69) | ITGB3ITGA2B | |
| SCHEMBL7307289 | 0.75 | ITGB3 (0.70) | ITGB3ITGA2B | |
| SCHEMBL9223657 | 0.75 | ITGB3 (0.57) | ITGB3ITGA2BKDM4EHTTNPC1 | |
| SCHEMBL9189037 | 0.75 | ITGB3 (0.54) | ITGB3ITGA2BKDM4EALOX15 | |
| SCHEMBL8407980 | 0.74 | F10 (0.60) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | claimed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | claimed |
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | disclosed |
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | disclosed |