Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 17/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302505 | 0.79 | ITGB3 (0.69) | ITGB3ITGA2B | |
| SCHEMBL7307202 | 0.74 | SIGMAR1 (0.34) | ITGB3ITGA2B | |
| SCHEMBL7304632 | 0.73 | ITGB3 (0.57) | ITGB3ITGA2BALDH1A1GFERTPSAB1 | |
| SCHEMBL7297075 | 0.73 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL9223657 | 0.71 | ITGB3 (0.57) | ITGB3ITGA2BALDH1A1GFERTPSAB1 | |
| SCHEMBL8384991 | 0.68 | ITGB3 (0.70) | ITGB3ITGA2B | |
| SCHEMBL7307289 | 0.68 | ITGB3 (0.70) | ITGB3ITGA2BTPSAB1 | |
| SCHEMBL8407980 | 0.66 | F10 (0.60) | ITGB3ITGA2BTPSAB1 | |
| SCHEMBL2344986 | 0.66 | ITGB3 (0.56) | ITGB3ITGA2BTPSAB1 | |
| SCHEMBL8693493 | 0.65 | ITGB3 (0.48) | ITGB3ITGA2BTPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | disclosed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | disclosed |