Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28329534 | 0.86 | PLK1 (0.53) | HDAC1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL4463757 | 0.85 | HDAC1 (0.58) | HDAC1HDAC6HDAC3HDAC8HDAC11 | |
| SCHEMBL21652228 | 0.82 | TRPV1 (0.64) | HDAC1HDAC6HDAC3HDAC8HDAC11 | |
| SCHEMBL1982935 | 0.77 | HDAC6 (0.78) | HDAC6HDAC3HDAC8HDAC11SMN1; SMN2 | |
| SCHEMBL7296335 | 0.77 | HDAC6 (0.78) | HDAC6HDAC3HDAC8HDAC11SMN1; SMN2 | |
| SCHEMBL7296065 | 0.75 | PKM (0.57) | HDAC1HDAC6HDAC3HDAC8HDAC11 | |
| SCHEMBL22103855 | 0.75 | MAPT (0.51) | HDAC1HDAC6HDAC3HDAC8HDAC11 | |
| SCHEMBL7296707 | 0.75 | KCNK9 (0.73) | HDAC6HDAC3HDAC8HDAC11SMN1; SMN2 | |
| SCHEMBL7292348 | 0.74 | RAB9A (0.62) | HDAC1HDAC6HDAC3HDAC8HDAC11 | |
| SCHEMBL3288511 | 0.74 | RAB9A (0.68) | HDAC1HDAC6HDAC3HDAC8HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |