Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300483 | 0.88 | MAPK8 (0.33) | KMT2ACA9ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7306055 | 0.82 | HDAC3 (0.37) | CA9 | |
| SCHEMBL7307448 | 0.77 | PGR (0.35) | HPGDCA9NR1H4ALDH1A1MAPT | |
| SCHEMBL185541 | 0.74 | KMT2A (0.39) | KMT2AHPGDCA9ALDH1A1MAPT | |
| SCHEMBL7314203 | 0.73 | KMT2A (0.33) | KMT2A | |
| SCHEMBL28073670 | 0.72 | CYP2E1 (0.32) | — | |
| SCHEMBL17987796 | 0.70 | KMT2A (0.54) | KMT2ACA9ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7307513 | 0.69 | CYP2D6 (0.35) | KMT2AHPGDCA9CNR1MAPT | |
| SCHEMBL7312968 | 0.69 | EPHX1 (0.32) | — | |
| SCHEMBL27680868 | 0.68 | LTA4H (0.39) | HPGDALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634396-B1 | Amino acid derivatives and their use as inhibitors of encephalinase | BIOPROJET SOC CIV (FR) | 1998-10-28 | — | — | EP | disclosed |
| EP-0634396-A1 | Amino acid derivatives and their use as inhibitors of encephalinase | SOCIETE CIVILE BIOPROJET (FR) | 1995-01-18 | — | — | EP | disclosed |