Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16309015 | 0.90 | KDM4E (0.69) | CCR8KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12470738 | 0.89 | KDM4E (0.67) | CCR8KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22895271 | 0.88 | KDM4E (0.77) | CCR8KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19620304 | 0.85 | KDM4E (0.63) | CCR8KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15564843 | 0.85 | KDM4E (0.65) | CCR8KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL608528 | 0.84 | ALDH1A1 (0.76) | CCR8KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12472388 | 0.84 | KDM4E (0.61) | CCR8KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12470988 | 0.84 | KDM4E (0.61) | CCR8KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12472412 | 0.84 | CCR8 (0.59) | CCR8KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12472730 | 0.84 | CCR8 (0.59) | CCR8KDM4EALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |