Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302798 | 0.80 | SPHK2 (0.44) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL7296963 | 0.79 | ACE (0.40) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL7297128 | 0.77 | CPT2 (0.44) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL7302058 | 0.77 | KLK7 (0.45) | TSHR | |
| SCHEMBL9658435 | 0.76 | SLC1A1 (0.44) | CTSLSLC1A3SLC1A1 | |
| SCHEMBL7296919 | 0.76 | LTA4H (0.38) | CTSLSLC1A3SLC1A1 | |
| SCHEMBL7296710 | 0.74 | NOS3 (0.47) | CTSLSLC1A3SLC1A1 | |
| SCHEMBL6359011 | 0.74 | SLC1A1 (0.46) | DPP8DPP9DPP7SLC1A3SLC1A1 | |
| SCHEMBL7303916 | 0.74 | CTSL (0.52) | CTSLITGB3ITGA2B | |
| SCHEMBL7338057 | 0.73 | ACE (0.38) | DPP4DPP8DPP9DPP7CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526877-A2 | Peptide aldehydes as antithrombotic agents | Bristol-Myers Squibb Company (US) | 1993-02-10 | — | — | EP | disclosed |