Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 17/20 | 0.48 |
| ▸ | MMP3 | P08254 | 12/20 | 0.48 |
| ▸ | MMP1 | P03956 | 10/20 | 0.48 |
| ▸ | MMP7 | P09237 | 6/20 | 0.46 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301616 | 0.89 | REN (0.48) | MMP2MMP3MMP1MMP7BIRC2 | |
| SCHEMBL7294738 | 0.82 | MMP2 (0.46) | MMP2MMP3MMP1MMP7BIRC2 | |
| SCHEMBL6443866 | 0.80 | MME (0.55) | MMP2MMP3MMP1 | |
| SCHEMBL6443858 | 0.80 | MME (0.55) | MMP2MMP3MMP1 | |
| SCHEMBL7293747 | 0.77 | PSMB5 (0.49) | MMP2MMP3MMP1MMP7BIRC2 | |
| SCHEMBL17553593 | 0.76 | REN (0.53) | MMP2MMP1 | |
| SCHEMBL6447062 | 0.76 | MME (0.54) | MMP2MMP3MMP1 | |
| SCHEMBL6447064 | 0.76 | MME (0.54) | MMP2MMP3MMP1 | |
| SCHEMBL6447060 | 0.76 | MME (0.54) | MMP2MMP3MMP1 | |
| SCHEMBL7294560 | 0.75 | REN (0.60) | MMP2MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989010751-A1 | FUNCTIONALIZED PEPTIDYL AMINODIOLS AND -TRIOLS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |
| EP-0341602-A2 | Renin-inhibiting functionalized peptidyl aminodiols and - triols | ABBOTT LABORATORIES (US) | 1989-11-15 | — | — | EP | disclosed |