Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.36 |
| ▸ | GPX4 | P36969 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432839 | 0.90 | ALDH1A1 (0.39) | TP53ALDH1A1RAB9ANPC1PAX8 | |
| SCHEMBL7309288 | 0.89 | TSHR (0.40) | TP53ALDH1A1RAB9ANPC1PAX8 | |
| SCHEMBL7309325 | 0.89 | ALDH1A1 (0.38) | TP53ALDH1A1RAB9ANPC1PAX8 | |
| SCHEMBL3535191 | 0.77 | USP2 (0.38) | TP53ALDH1A1NPC1SMN1; SMN2CYP3A4 | |
| SCHEMBL7303328 | 0.77 | NR4A2 (0.39) | TP53ALDH1A1RAB9ANPC1PAX8 | |
| SCHEMBL7297468 | 0.75 | DRD3 (0.41) | ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL7299287 | 0.75 | ALDH1A1 (0.40) | ALDH1A1RAB9ANPC1PAX8CA12 | |
| SCHEMBL7298470 | 0.75 | ALDH1A1 (0.40) | TP53ALDH1A1RAB9ANPC1CA12 | |
| SCHEMBL7298114 | 0.74 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2LMNATDP1KDM4E | |
| SCHEMBL7302756 | 0.72 | SMN1; SMN2 (0.43) | TP53ALDH1A1SMN1; SMN2LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304560-A | Treating CNS disorders; dopamine receptor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0481342-A1 | Quinazoline derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |