Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302910 | 0.89 | TP53 (0.44) | TSHRALDH1A1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL9432839 | 0.88 | ALDH1A1 (0.39) | TSHRALDH1A1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7309325 | 0.87 | ALDH1A1 (0.38) | TSHRALDH1A1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7298114 | 0.80 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2KDM4EMAPTMEN1 | |
| SCHEMBL7301503 | 0.76 | HTR7 (0.43) | ALDH1A1KDM4EMAPT | |
| SCHEMBL7298470 | 0.76 | ALDH1A1 (0.40) | TSHRALDH1A1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7299287 | 0.76 | ALDH1A1 (0.40) | TSHRALDH1A1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7303328 | 0.75 | NR4A2 (0.39) | TSHRALDH1A1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7302767 | 0.70 | SMN1; SMN2 (0.45) | TSHRALDH1A1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL7302756 | 0.70 | SMN1; SMN2 (0.43) | TSHRALDH1A1SMN1; SMN2KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304560-A | Treating CNS disorders; dopamine receptor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0481342-A1 | Quinazoline derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |